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Updated: Oct 21, 2025

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
Recurrent spontaneous pneumothoraxes as a complication of osteosarcoma metastases: a case report
Mark Kleedehn1, Sandor Krisztian Kovacs2, Brody Fitzpatrick3
1Assistant Professor, Fellowship Director, Department of Interventional Radiology, University of Wisconsin- Madison School of Medicine and Public Health, Madison, Wisconsin.
Abstract:
Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Osteosarcomas are highly aggressive tumors that historically have had a dismal prognosis. However, the survival rate has improved significantly with the addition of adjuvant and neoadjuvant chemotherapy. Here, we present a case report of a 13-year-old male with a history of a left humeral osteosarcoma whose course was complicated by recurrent sarcoma-related pneumothoraces. Despite recurrent pneumothoraces being a relatively uncommon complication of osteosarcoma, they present a great challenge to providing treatment that optimizes outcomes and quality of life for patients.
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