Primary Aortic Angiosarcoma: A Review of Two Cases Highlighting Unique Imaging and Clinical Characteristics
Case H Keltner1, Ana Paula Santos Lima1, Malinda West1
1School of Medicine (C.H.K.), Department of Diagnostic Radiology (A.P.S.L., C.F.), Knight Cancer Institute (M.W., L.E.D.), and Department of Orthopaedics & Rehabilitation (K.R.G.), Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239; and Operative Care Division, Portland VA Medical Center, Portland, Ore (K.R.G.).
Primary angiosarcoma of the aorta, a rare vascular tumor, can present with diffuse arterial tumor emboli causing delayed diagnosis. Careful imaging interpretation is crucial for aortic lesions, especially without atherosclerosis or vasculitis.
Area of Science:
- Vascular Oncology
- Diagnostic Imaging
Background:
- Angiosarcomas are rare vascular tumors originating from the aorta.
- Primary aortic angiosarcomas are exceptionally uncommon.
Observation:
- Two cases of primary angiosarcoma of the aorta are presented.
- These cases highlight initial manifestations and complications from diffuse arterial tumor emboli.
Findings:
- Diffuse arterial tumor emboli can lead to delayed cancer diagnosis.
- Imaging findings in aortic lesions must be correlated with clinical context, differentiating from atherosclerosis or vasculitis.
Implications:
- Emphasizes the importance of considering rare neoplasms in aortic lesions.
- Highlights the diagnostic challenges and potential complications of primary aortic angiosarcoma.
- Suggests a need for integrated diagnostic approaches in evaluating aortic pathologies.
Related Concept Videos
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...


