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Recent progress in the design of analytical methods based on nanozymes
Qingqing Wang1, Shaoqin Liu1, Zhiyong Tang2
1School of Chemistry and Chemical Engineering, Key Laboratory of Microsystems and Microstructures Manufacturing (Ministry of Education), Harbin Institute of Technology, Harbin 150001, China. shaoqinliu@hit.edu.cn.
Nanozymes, nanomaterials with enzyme-like activity, offer a stable, cost-effective alternative to natural enzymes for developing advanced analytical platforms. This review highlights their use in signal amplification for detecting diverse analytes.
Area of Science:
- Biotechnology
- Materials Science
- Analytical Chemistry
Background:
- Nanozymes possess intrinsic enzyme-like catalytic properties.
- They offer advantages over natural enzymes, including stability, low cost, and tunability.
- Nanozymes are emerging as key components in advanced analytical systems.
Purpose of the Study:
- To review recent advances in nanozyme design strategies for sensing.
- To summarize the application of nanozyme catalytic activity in signal amplification for analyte detection.
- To discuss the progress and future prospects of nanozyme-based analytical methods.
Main Methods:
- Focus on design strategies for nanozyme-based signal amplification.
- Summarize analytical systems utilizing nanozymes for various analyte detections.
- Review recent literature on nanozyme applications in sensing.
Main Results:
- Nanozymes enable robust and versatile analytical platforms.
- Catalytic signal amplification by nanozymes enhances detection sensitivity.
- Successful applications demonstrated for detecting ions, small biomolecules, and biomacromolecules.
Conclusions:
- Nanozymes are potent tools for developing novel analytical platforms.
- Further research into nanozyme design and application is warranted.
- Nanozyme-based methods present significant opportunities for future analytical advancements.
