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Related Experiment Videos

NIH's Helping to End Addiction Long-termSM Initiative (NIH HEAL Initiative) Clinical Pain Management Common Data

Laura Dover Wandner1, Anthony F Domenichiello2, Jennifer Beierlein1

  • 1National Institute of Neurological Disorders and Stroke, Bethesda, Maryland.

The Journal of Pain
|September 11, 2021
PubMed
Summary

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Developing consensus on core outcome sets of domains for acute, the transition from acute to chronic, recurrent/episodic, and chronic pain: results of the INTEGRATE-pain Delphi process.

EClinicalMedicine·2023

The NIH HEAL Initiative established standardized data collection for clinical pain research. Nine core pain domains and specific questionnaires were selected to improve data uniformity and future research in pain management.

Area of Science:

  • Pain research
  • Clinical data standardization
  • Public health initiatives

Background:

  • The national opioid crisis necessitates improved pain management strategies.
  • The National Institutes of Health (NIH) HEAL Initiative aims to accelerate solutions for the opioid crisis.
  • Standardized data collection is crucial for effective clinical pain research.

Purpose of the Study:

  • To implement a Common Data Element (CDE) program within the NIH HEAL Initiative.
  • To establish standardized methods for collecting data in NIH-funded clinical pain studies.
  • To identify core pain domains and validated questionnaires for uniform data collection.

Main Methods:

  • Conducted multiple literature reviews.
  • Consulted with internal and external experts in pain research.
Keywords:
DataHEALHarmonizationPainPatient Reported Outcomes

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  • Engaged with investigators funded by the NIH HEAL Initiative.
  • Selected 9 core pain domains and associated questionnaires.

    • Main Results:

    • Identified 9 essential pain domains for clinical pain studies.
    • Selected specific questionnaires for uniform assessment of acute and chronic pain.
    • Developed supplemental questionnaires for study-specific outcomes.
    • Ensured data standardization across adult and pediatric populations.

    Conclusions:

    • The chosen core domains and questionnaires will standardize clinical pain data.
    • Standardized data will enhance secondary data analysis and future research.
    • This initiative supports informed clinical practice decisions and policymaking.
    • Uniform data collection is vital for addressing the opioid crisis through pain management.