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Inflammatory Bowel Disease V: Surgical Management

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...

Inflammatory Bowel Disease II: Crohn's Disease

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...

Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF

Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF

Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

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Robotics in Surgery: A Modular Robotic Platform Driven Gastric Wedge Resection

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Robotic Surgery in Crohn's Disease.

Drew Gunnells¹, Jamie Cannon¹

¹Division of Gastrointestinal Surgery, University of Alabama, Birmingham, Alabama.

Clinics in Colon and Rectal Surgery

|September 13, 2021

Summary

Robotic surgery offers a minimally invasive option for Crohn's disease patients, overcoming challenges associated with traditional laparoscopy. This approach enables complex cases of terminal ileal Crohn's disease to benefit from advanced surgical techniques.

Keywords:

Crohn's disease robotic surgery

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Area of Science:

Gastroenterology
Surgical Oncology
Minimally Invasive Surgery

Background:

Crohn's disease surgery faces challenges due to inflammation.
Minimally invasive colorectal surgery improves patient outcomes.
Laparoscopic adoption in Crohn's disease is limited.

Purpose of the Study:

To describe a robotic-assisted surgical approach for terminal ileal Crohn's disease.
To highlight the potential of robotic surgery in complex Crohn's disease cases.

Main Methods:

Robotic-assisted surgical technique.
Focus on terminal ileal Crohn's disease.

Main Results:

Robotic surgery facilitates minimally invasive procedures in complex Crohn's disease.
Potential for improved outcomes in Crohn's disease patients undergoing robotic surgery.

Conclusions:

Robotic-assisted surgery is a viable option for terminal ileal Crohn's disease.
This approach may expand minimally invasive options for Crohn's disease patients.