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Updated: Oct 20, 2025

The Mesenteric Lymph Duct Cannulated Rat Model: Application to the Assessment of Intestinal Lymphatic Drug Transport
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An update on oral drug delivery via intestinal lymphatic transport

Zichen Zhang1, Yi Lu1, Jianping Qi1

  • 1Key Laboratory of Smart Drug Delivery of MOE, School of Pharmacy, Fudan University, Shanghai 201203, China.

Acta Pharmaceutica Sinica. B
|September 15, 2021
PubMed

Keywords:
ACQ, aggregation-caused quenchingASRT, apical sodium-dependent bile acid transporterAUC, area under curveBCS, biopharmaceutics classification systemCM, chylomicronChylomicronDC, dendritic cellDDT, dichlorodiphenyltrichloroethaneDTX, docetaxelDrug absorptionDrug carriersDrug deliveryFA, fatty acidFAE, follicle-associated epitheliaFRET, Föster resonance energy transferGIT, gastrointestinal tractHBsAg, hepatitis B surface antigenHIV, human immunodeficiency virusLDL, low-density lipoproteinLDV, Leu-Asp-ValLDVp, LDV peptidomimeticLymphatic transportM cell, microfold cellsMG, monoglycerideMPA, mycophenolic acidMPS, mononuclear phagocyte systemMicrofold cellNanoparticlesOA, oleateOralPCL, polycaprolactonePEG-PLA, polyethylene glycol-poly(lactic acid)PEI, polyethyleneiminePLGA, poly(lactic-co-glycolic acid)PVA, poly(vinyl alcohol)RGD, Arg-Gly-AspRGDp, RGD peptidomimeticSEDDS, self-emulsifying drug delivery systemSLN, solid lipid nanoparticlesSNEDDS, self-nanoemulsifying drug delivery systemTEM, transmission electron microscopyTG, triglycerideTPGS, D-α-tocopherol polyethylene glycol 1000 succinateTU, testosterone undecanoateWGA, wheat germ agglutininYCW, yeast cell wall

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