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Updated: Oct 20, 2025

Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)
Ilaria Testi1, Sandra Vermeirsch1, Carlos Pavesio2
1Department of Uveitis, Moorfields Eye Hospital, National Health Service Foundation Trust, 162 City Rd, Old Street, London, EC1V 2PD, UK.
Background:
Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing a better characterization of the morphology of this condition.
Methods:
Narrative review.
Results:
In this review, a comprehensive overview of clinical features, imaging findings, treatment management, and long-term outcomes of patients with APMPPE will be provided.
Conclusions:
Although APMPPE was originally believed to be a self-limited condition with a good prognosis, the disease can be recurrent and result in significant loss of vision function. Fundus imaging plays an important role in the diagnosis and management of the disease, allowing to evaluate response to treatment and onset of complications.

