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Single-cell tracking reveals super-spreading brain cancer cells with high persistence

Aimilia Nousi1, Maria Tangen Søgaard1, Mélanie Audoin1

  • 1The Niels Bohr Institute, University of Copenhagen, Blegdamsvej 17, DK-2100, Copenhagen O, Denmark.

Biochemistry and Biophysics Reports
|September 20, 2021
PubMed
Summary

Single cell migration in brain tumors is highly directional and persistent, unaffected by Matrigel concentration. A subpopulation of super-spreading cells exhibits significantly longer persistence, revealing tumor cell heterogeneity.

Keywords:
Diffusion modelsGlioblastomaInvasion assaySingle-cell tracking

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