Related Experiment Video
Updated: Oct 19, 2025

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
Two Cases of Pseudoelevation of Plasma D-Dimer Levels
Background:
D-dimer is a molecular marker of fibrin degradation and fibrinolytic system activation and is an effective indicator for early diagnosis of thrombotic diseases, monitoring of thrombolytic therapy, and efficacy evaluation; therefore, the accuracy of D-dimer test results is of great significance to the diagnosis and treatment of diseases in clinical practice.
Methods:
This paper reports two cases of pseudoelevation of plasma D-dimer levels by different test systems.
Results:
In case 1, the abnormal increases in the results of the ACL TOP 700 analyzer were considered to be the pseudoelevation caused by interferences, and the abnormal increases in the STA-R Max results were considered to be the pseudoelevation caused by interferences in case 2.
Conclusions:
Laboratories should be equipped with two different brands of test systems and reagents to identify suspicious test results in a timely manner and avoid adverse events.
Related Concept Videos
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis III: Interprofessional Care
Pulmonary Embolism III: Nursing Management
Pulmonary Embolism I: Introduction
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

