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Updated: Oct 18, 2025
06:09
Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
7.1K
Breath Biomarkers in Diagnostic Applications
Y Lan Pham1,2, Jonathan Beauchamp1
1Department of Sensory Analytics and Technologies, Fraunhofer Institute for Process Engineering and Packaging IVV, Giggenhauser Straße 35, 85354 Freising, Germany.
Molecules (Basel, Switzerland)
|September 28, 2021
Summary
Exhaled breath analysis offers a non-invasive method for diagnosing diseases and assessing health. This review explores current and future breath tests utilizing metabolomics for physiological insights.
Area of Science:
- Analytical Chemistry
- Biochemistry
- Physiology
Background:
- Exhaled human breath contains chemical compounds reflecting physiological states, disease conditions, and environmental exposures.
- Metabolomics research has advanced the exploration of metabolic profiles within breath.
- Breath analysis is non-invasive, convenient, and readily available, making it ideal for metabolomics.
Purpose of the Study:
- To review the concept and applications of breath analysis.
- To discuss established breath-based tests targeting endogenous and exogenous compounds.
- To explore the physiological basis and development of breath tests.
Main Methods:
- Review of current literature on breath analysis and metabolomics.
- Discussion of established breath tests and their targeted biomarkers.
- Analysis of physiological production of breath biomarkers.
Main Results:
- Several breath-based tests are established and in clinical use for diagnosing conditions.
- Breath biomarkers are linked to specific physiological processes and diseases.
- The review covers the development and implementation of these tests.
Conclusions:
- Breath analysis is a promising non-invasive diagnostic tool.
- Further research into prospective tests will expand the utility of breath analysis.
- The future of breath research involves refining existing tests and developing new applications.
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