Related Experiment Video
Updated: Oct 18, 2025

A Cognitive Paradigm to Investigate Interference in Working Memory by Distractions and Interruptions
Published on: July 16, 2015
Inhibitory Abilities in Individuals with Down Syndrome: Investigation of Interference Suppression Using an Adapted
Martina Fontana1, Maria Carmen Usai2, Maria Chiara Passolunghi1
1Department of Life Sciences, University of Trieste, Trieste, Italy.
Abstract:
Only a few studies have investigated inhibitory sub-components in individuals with Down syndrome (DS). This study investigates interference suppression, through global-local processes, in 50 people with DS matched for mental age (MA) with 63 typically developing children (MA = 23.6 and 6.8 years respectively). We adapted and administered a non-verbal Navon-shape task with high-familiarity symbols. For both groups, results showed equal performance on global vs. local items in the congruent condition, whereas significantly better performance on global conditions when faced with incongruent items. A greater impairment in incongruent responses emerged for both groups and more so for individuals with DS.

