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Metaplastic breast carcinoma with extensive osseous differentiation
Shalaka Khade1, Sudeep Khera1, Poonam Elhence1
1All India Institute of Medical Sciences, Department of Pathology and Lab Medicine, Jodhpur, India.
Autopsy & Case Reports
|October 4, 2021
Summary
Metaplastic breast carcinoma, a rare invasive breast cancer subtype, can present diagnostic challenges. This case highlights a rare variant with osseous differentiation, initially misdiagnosed as a phyllodes tumor.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Metaplastic breast carcinoma is a rare invasive breast cancer subtype.
- Metaplastic carcinoma with osseous differentiation is exceptionally uncommon.
- Heterogeneous microscopy and varied clinical/radiological features pose diagnostic challenges.
Observation:
- A 43-year-old female presented with a recurrent breast lump.
- Clinical diagnosis suggested a phyllodes tumor.
- The lesion exhibited varied clinical and radiological features.
Findings:
- Histopathological examination revealed metaplastic carcinoma with extensive osseous differentiation.
- This finding contrasts with the initial clinical diagnosis.
- The case underscores the importance of histopathology in diagnosing rare breast cancers.
Implications:
- Accurate diagnosis of metaplastic breast carcinoma is crucial for appropriate treatment.
- Osseous differentiation in metaplastic carcinoma requires specific consideration.
- Enhanced awareness of rare breast cancer subtypes can improve patient outcomes.
