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Orbital mucormycosis - Post SARS-CoV-2 sequelae
Hafsa Mobeen1,2, Naveed Ullah Khan1,3, Muhammad Hassan1,3
1Shaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, Pakistan.
Abstract:
Multisystem involvement has not been uncommon in SARS-CoV-2 infection. There has been reports of devastating neurological complication both during and after the infection. Here we present a rare case of sino-orbital mucormycosis, diagnosis of which was confirmed on histopathology. Our patient presented with headache, 18 days after her recovery from SARS-CoV-2 infection and was extensively worked up for the cause. Initially she was treated as a severe sinusitis but failure to response to antibiotics treatment warranted for further investigations and imaging. Our patient had to undergo right eye enucleation plus debridement under general anesthesia. She is currently on anti-fungal treatment as advised by infectious disease department.
Insights
A rare sino-orbital mucormycosis case occurred 18 days post-SARS-CoV-2 infection. This fungal infection required surgical intervention and ongoing antifungal treatment.
Area of Science:
- Infectious Diseases
- Ophthalmology
- Neurology
Background:
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can lead to multisystem complications.
- Neurological complications following SARS-CoV-2 infection have been reported.
- Mucormycosis is a rare but serious fungal infection.
Observation:
- A patient presented with headache 18 days after recovering from SARS-CoV-2.
- Initial diagnosis was severe sinusitis, but antibiotic treatment failed.
- Further investigations and imaging were necessary due to lack of response.
Findings:
- The patient was diagnosed with sino-orbital mucormycosis, confirmed by histopathology.
- Surgical intervention, including right eye enucleation and debridement, was performed.
- The patient is currently undergoing antifungal treatment.
Implications:
- This case highlights a rare post-SARS-CoV-2 complication.
- Early diagnosis and multidisciplinary management are crucial for sino-orbital mucormycosis.
- Further research into the link between SARS-CoV-2 and opportunistic fungal infections is warranted.
