[Pathology of pancreatic tumors]

Pancreatic cancer in the narrower sense is defined as pancreatic ductal adenocarcinoma (PDAC), which accounts for 95% of malignancies of the pancreas. The tumor has a very poor prognosis, one of the reasons being that it is often only recognized at an advanced, already metastatic stage. Another reason is that although oncotherapy has developed rapidly in recent decades, there has been no significant improvement in the treatment of these tumors. Based on Hungarian and international analyses, we can expect an increase in the number of patients in the coming decades, so research in any field of medicine is of paramount importance for early diagnosis and the development of more effective treatment strategies. However, it is important to know the other benign and malignant exocrine and neuroendocrine tumors, the precursor lesions, as the basic condition for proper treatment is an accurate pathological diagnosis. The summary presents the pathological diversity of tumors, detailing their macroscopic, microscopic, and immunohistochemical characteristics.