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Updated: Oct 17, 2025

A Structured Approach to Extubation in Mechanically Ventilated Rats
Published on: July 18, 2025
A Quality Improvement Approach to Reduce Unplanned Extubation in the NICU While Avoiding Sedation and Restraints
C Briana Bertoni1,2, Thomas Bartman3, Gregory Ryshen3
1Division of Outreach Medicine, Children's National Medical Center, Washington, D.C.
Reducing unplanned extubation in NICU infants is achievable through standardized endotracheal tube securement. This quality improvement project focused on minimizing adverse events while promoting neurodevelopmental care.
Area of Science:
- Neonatal Intensive Care
- Patient Safety
- Quality Improvement
Background:
- Unplanned extubation (UE) is a frequent adverse event in neonatal intensive care units (NICUs).
- UE can lead to serious complications, including airway trauma and increased mortality.
- The NICU aimed to optimize neurodevelopmental outcomes by encouraging skin-to-skin care and discouraging sedation/restraints for intubated infants.
Purpose of the Study:
- To decrease the rate of unplanned extubation (UE) in intubated infants.
- To reduce UE from 1.85 to 1.5 per 100 endotracheal tube (ETT) days.
- To implement a quality improvement initiative within a neurodevelopmentally focused NICU setting.
Main Methods:
- A multidisciplinary team conducted biweekly reviews of UE events, categorizing them as preventable or nonpreventable.
- Key interventions included assigning a single process owner for UE reporting and standardizing endotracheal tube (ETT) securement procedures.
- Utilizing two clinical staff members during patient and/or ETT manipulation was implemented.
Main Results:
- Initial enhanced detection led to a temporary increase in UE rates (1.85 to 3.26 per 100 ETT days).
- Identification of preventable events and staff empowerment reduced UE frequency to 2.03 per 100 ETT days.
- Standardizing ETT taping methods initially caused a spike due to non-compliance, but improved securement methods led to favorable trending.
Conclusions:
- Reducing UE in a NICU that prioritizes neurodevelopmental care and avoids sedation/restraints presents unique challenges.
- A multidisciplinary quality improvement approach, coupled with accurate event capture, effectively reduced UE rates.
- Standardization of endotracheal tube securement proved to be the most impactful intervention for decreasing UE.
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