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[Study on warfarin medication checklist for improving patient compliance].
1Department of Pharmacy, Shanghai Tongren Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200336, China.
Summary
Clinical pharmacists using a warfarin checklist improved patient medication compliance and follow-up regularity. Better compliance was linked to shorter warfarin therapy duration, fewer comorbidities, and lower bleeding risk.
Area of Science:
- Pharmacology
- Clinical Pharmacy
- Patient Adherence
Background:
- Warfarin medication management is complex, requiring careful patient adherence for efficacy and safety.
- Poor medication compliance in warfarin therapy can lead to adverse events like bleeding or thrombosis.
- Clinical pharmacists play a role in optimizing medication management and patient education.
Purpose of the Study:
- To evaluate the impact of a warfarin medication checklist used by clinical pharmacists on patient medication compliance.
- To investigate the correlation between warfarin medication compliance and factors such as bleeding risk, comorbidities, and therapy duration.
Main Methods:
- A randomized controlled study involving 147 inpatients receiving warfarin.
- Intervention group received targeted education using a warfarin checklist; control group received routine education.
- Medication compliance assessed using the Morisky Medication Adherence Scale; correlations analyzed via Spearman analysis.
Main Results:
- The intervention group demonstrated significantly better follow-up regularity (P<0.001) and medication compliance (P<0.001) compared to the control group.
- Warfarin compliance was negatively correlated with duration of warfarin therapy (R=-0.275, P=0.027), number of comorbidities (R=-0.335, P=0.004), and bleeding risk (R=-0.433, P<0.001).
Conclusions:
- Utilizing a warfarin medication checklist by clinical pharmacists enhances patient medication compliance.
- Improved compliance is associated with reduced duration of warfarin therapy, fewer comorbidities, and lower bleeding risk.
- Clinical pharmaceutical care is crucial for improving warfarin treatment outcomes in patients with chronic diseases.
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