Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Beams with Unsymmetric Loadings01:17

Beams with Unsymmetric Loadings

198
Analyzing a supported beam under unsymmetrical loadings is essential in structural engineering to understand how beams respond to varied force distributions. This analysis involves calculating the deflection and identifying points where the slope of the beam is zero, which are crucial for ensuring structural stability and functionality.
The first moment-area theorem determines the slope at any point on the beam. This theorem indicates that the change in slope between two points on a beam...
198
Beams with Symmetric Loadings01:15

Beams with Symmetric Loadings

264
The moment-area method is an analytical tool used in structural engineering to determine the slope and deflection of beams under various loads. Consider a cantilever with a concentrated load and moment at the free end. The first step is constructing a free-body diagram to calculate the reactions at the fixed end. Next, the bending moment diagram is plotted to visualize how the bending moment varies along the beam's length, focusing on points where the bending moment equals zero.
The M/EI...
264
Prismatic Beams: Problem Solving01:15

Prismatic Beams: Problem Solving

243
In the design of a supported timber beam subjected to a distributed load, both the beam's physical dimensions and the timber's characteristics, such as its grade and species, are critical. These factors determine the allowable stress values, which are crucial for calculating the necessary beam depth to ensure structural integrity and safety.
The design begins with analyzing the beam as a free body to identify moments and force balances, thereby determining support reactions. Next, the...
243
Multimachine Stability01:25

Multimachine Stability

251
Multimachine stability analysis is crucial for understanding the dynamics and stability of power systems with multiple synchronous machines. The objective is to solve the swing equations for a network of M machines connected to an N-bus power system.
In analyzing the system, the nodal equations represent the relationship between bus voltages, machine voltages, and machine currents. The nodal equation is given by:
251
Bioequivalence: Overview01:16

Bioequivalence: Overview

1.3K
Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
1.3K
Bioequivalence studies: Biowaivers01:13

Bioequivalence studies: Biowaivers

23
Body:In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...
23

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SARS-CoV-2 mRNA Vaccination Improved Survival in NSCLC Treated With Radiotherapy.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer·2026
Same author

Simulated online adaptive radiotherapy on C-arm linacs: Integrating high resolution cone-beam CT into abdominal stereotactic body radiation therapy.

Journal of applied clinical medical physics·2026
Same author

Development and implementation of an MRI-only simulation, planning, and treatment workflow for prostate radiotherapy using synthetic CT on MR-linac.

Journal of applied clinical medical physics·2026
Same author

Detection of the Linac Jaw face angle misalignment using high energy electron beam symmetry.

Journal of applied clinical medical physics·2025
Same author

AAPM working group on cybersecurity report 438: A white paper on cybersecurity management for business continuity in radiology and radiation therapy.

Journal of applied clinical medical physics·2025
Same author

A Pilot Study of Computed Tomography Simulator Downtime at an African Cancer Conference: Survey Results From AORTIC 2023.

International journal of radiation oncology, biology, physics·2025

Related Experiment Video

Updated: Oct 17, 2025

Sample Preparation and Experimental Design for In Situ Multi-Beam Transmission Electron Microscopy Irradiation Experiments
08:31

Sample Preparation and Experimental Design for In Situ Multi-Beam Transmission Electron Microscopy Irradiation Experiments

Published on: June 27, 2022

1.9K

Interinstitutional beam model portability study in a mixed vendor environment.

Sean P Frigo1, Jared Ohrt2, Yelin Suh2

  • 1Department of Human Oncology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.

Journal of Applied Clinical Medical Physics
|October 13, 2021
PubMed
Summary
This summary is machine-generated.

A Varian TrueBeamSTx 6 MV flattened beam model in RayStation was successfully implemented at a new institution. Minimal adjustments allowed validation for intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) deliveries.

Keywords:
RayStationTrueBeambeam modelcommissioningparameter value optimizationportabilityvalidation

More Related Videos

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
07:13

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

1.4K
Operation of the Collaborative Composite Manufacturing CCM System
10:09

Operation of the Collaborative Composite Manufacturing CCM System

Published on: October 1, 2019

6.8K

Related Experiment Videos

Last Updated: Oct 17, 2025

Sample Preparation and Experimental Design for In Situ Multi-Beam Transmission Electron Microscopy Irradiation Experiments
08:31

Sample Preparation and Experimental Design for In Situ Multi-Beam Transmission Electron Microscopy Irradiation Experiments

Published on: June 27, 2022

1.9K
Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
07:13

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

1.4K
Operation of the Collaborative Composite Manufacturing CCM System
10:09

Operation of the Collaborative Composite Manufacturing CCM System

Published on: October 1, 2019

6.8K

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Radiotherapy Technology

Background:

  • Implementing and validating treatment planning system (TPS) models across different institutions is crucial for consistent radiotherapy delivery.
  • A 6 MV flattened beam model for Varian TrueBeamSTx in RayStation was previously developed and validated at one institution.
  • Inter-institutional model implementation requires understanding potential variations in machine output and validation protocols.

Purpose of the Study:

  • To implement and validate a pre-existing 6 MV flattened beam model for a Varian TrueBeamSTx system in RayStation at a second institution.
  • To assess the model's performance with minimal parameter adjustments for machine output differences.
  • To evaluate the model's applicability across diverse treatment plans and measurement scenarios.

Main Methods:

  • The existing RayStation model for a Varian TrueBeamSTx 6 MV flattened beam was transferred to a second institution.
  • Parameter adjustments were limited to accommodating the specific machine output at the new institution.
  • Validation was performed according to Medical Physics Professional Guidance (MPPG) 5.a. recommendations, focusing on IMRT and VMAT plans.

Main Results:

  • The implemented model passed validation with only minor adjustments for machine output differences.
  • Successful validation was achieved across a wide range of treatment plans, measurement devices, and personnel.
  • The model demonstrated robustness in delivering accurate dose distributions for complex IMRT and VMAT deliveries.

Conclusions:

  • A single template model can be effectively utilized in the RayStation treatment planning system for matched Varian TrueBeamSTx machines.
  • This approach is feasible even in a mixed-vendor environment, simplifying model implementation across institutions.
  • Minimal site-specific calibration is sufficient for successful inter-institutional deployment of TPS beam models.