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Published on: March 29, 2022
Prevalence of pseudophakia: U.S. population-based study
Ellen A Erie1, David O Hodge, Michael A Mahr
1From Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota (Erie, Mahr); Department of Quantitative Health Science, Mayo Clinic, Jacksonville, Florida (Hodge).
Pseudophakia prevalence in Olmsted County, Minnesota, surged 590% over 30 years, reaching 6.5% in 2018. Most older adults, especially those 85+, are pseudophakic, benefiting from cataract surgery.
Area of Science:
- Ophthalmology
- Public Health
- Epidemiology
Background:
- Pseudophakia, the state of having an intraocular lens after cataract surgery, is increasingly common due to aging populations and advancements in surgical techniques.
- Understanding the prevalence and trends of pseudophakia is crucial for healthcare planning and resource allocation.
Purpose of the Study:
- To determine the current prevalence and temporal trends of pseudophakia in a well-defined U.S. population.
- To calculate pseudophakia prevalence and associated mortality rates in Olmsted County, Minnesota, from 1988 to 2018.
Main Methods:
- A population-based cohort study utilizing the Rochester Epidemiology Project (REP) databases.
- Identification of pseudophakia cases in Olmsted County residents between 1988 and 2018.
- Calculation of age- and sex-specific prevalence rates and assessment of trends using Poisson regression; mortality rates estimated via Kaplan-Meier analysis.
Main Results:
- In 2018, 6.5% of Olmsted County residents (10,024 individuals) were pseudophakic.
- Prevalence increased significantly over 30 years (590%) and 10 years (67%), with higher rates in women and older age groups (88% of those 85+).
- Pseudophakia was associated with lower all-cause mortality compared to the general population.
Conclusions:
- Pseudophakia is highly prevalent in older adults, with most individuals aged 75 and above being pseudophakic in at least one eye by 2018.
- These findings highlight the significant impact of cataract surgery on the visual status and health outcomes of the aging population.
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