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Tropicamide and anaphylaxis: A case report

Nazife Sefi-Yurdakul1, Özlem Sancakli2

  • 1Department of Ophthalmology, Başkent University Zübeyde Hanım Hospital, İzmir, Turkey.

Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society
|October 20, 2021
PubMed

Insights

Tropicamide eye drops, used for infant eye exams, can rarely cause severe anaphylaxis and circulatory failure. Prompt medical intervention is crucial for managing these life-threatening complications.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Anesthesiology

Background:

  • Pediatric eye examinations require cycloplegic agents for accurate refraction.
  • Tropicamide is commonly used for its mydriatic and cycloplegic properties.

Observation:

  • A 6-month-old infant developed anaphylaxis, respiratory, and circulatory failure shortly after receiving tropicamide (1%) eye drops.
  • The infant required immediate emergency medical intervention.

Findings:

  • The infant's condition stabilized, and symptoms improved within minutes of treatment initiation.
  • This case highlights a rare but severe adverse reaction to tropicamide in an infant.

Implications:

  • Ophthalmologists and pediatricians should be aware of the potential for severe systemic reactions to tropicamide.
  • Careful patient selection and preparedness for emergency management are essential when administering tropicamide to infants.

Keywords:
Tropicamideanaphylaxiscycloplegia

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