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Published on: February 8, 2017
Novel Micro- and Nanocellulose-Based Delivery Systems for Liposoluble Compounds
Francisca Casanova1, Carla F Pereira1, Alessandra B Ribeiro1
1CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Micro- and nanocellulose are promising carriers for improving the delivery of poorly soluble bioactive compounds. These cellulose-based systems enhance stability and bioavailability for various applications.
Area of Science:
- Biomaterials Science
- Drug Delivery Systems
- Nanotechnology
Background:
- Poor aqueous solubility of bioactive compounds limits formulation development.
- Liposoluble compounds with biological activity face challenges in stability and bioavailability.
- Enabling delivery strategies and novel carrier materials are needed to overcome these limitations.
Purpose of the Study:
- To review the current research on micro- and nanocellulose-based delivery systems.
- To focus on the release of liposoluble bioactive compounds using these systems.
- To provide a comprehensive overview of their chemistry, preparation, properties, and applications.
Main Methods:
- Literature review of micro- and nanocellulose-based delivery systems.
- Analysis of studies focusing on liposoluble bioactive compound release.
- Discussion of safety, toxicity, and gastrointestinal impact.
Main Results:
- Micro- and nanocellulose exhibit unique features as promising carriers.
- These systems show potential for enhancing the delivery of liposoluble bioactive compounds.
- The review covers preparation, properties, applications, and safety aspects.
Conclusions:
- Micro- and nanocellulose-based delivery systems offer significant promise for various applications.
- Further research is needed to fully understand safety, toxicity, and in vivo performance.
- These materials represent a hopeful avenue for overcoming solubility and bioavailability challenges.
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