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Evolving Concepts of Type 2 Diabetes Management.
Layla A Abushamat1, Jane E B Reusch2
1Division of Endocrinology, Metabolism, and Diabetes, University of Colorado School of Medicine, MS 8106, 12801 East 17th Avenue, Room 7103, Aurora, CO 80045, USA.
The Medical Clinics of North America
|October 24, 2021
Summary
This review covers current glucose-lowering diabetes medications, emphasizing patient-centered care. Shared decision-making should consider patient factors and new evidence for cardiorenal protection.
Area of Science:
- Endocrinology
- Pharmacology
- Patient-Centered Care
Background:
- Current diabetes medications offer various glucose-lowering mechanisms.
- Patient-centered care necessitates individualized treatment selection.
- Evolving evidence impacts antihyperglycemic agent recommendations.
Purpose of the Study:
- To outline available glucose-lowering diabetes medications.
- To highlight characteristics for shared decision-making in diabetes therapy.
- To integrate recent evidence on cardiorenal protection.
Main Methods:
- Review of current antihyperglycemic agents.
- Analysis of medication characteristics relevant to patient factors.
- Consideration of FDA guidance and recent clinical trial data.
Main Results:
- Multiple classes of glucose-lowering medications exist with distinct profiles.
- Patient-specific factors (weight, hypoglycemia risk, cost, social determinants, literacy) are crucial.
- Cardiovascular and cardiorenal benefits/risks guide modern agent selection.
Conclusions:
- Effective diabetes management requires shared decision-making tailored to individual patients.
- Antihyperglycemic agents should be chosen considering both glucose control and cardiorenal outcomes.
- A patient-centered approach, informed by updated evidence, ensures durable and effective diabetes therapy.
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