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Updated: Oct 15, 2025

Measuring Relative Insulin Secretion using a Co-Secreted Luciferase Surrogate
Published on: June 25, 2019
Comparative efficacy and safety of basal insulins: A review
Hernando Vargas-Uricoechea1, Pablo Aschner2
1Director of Metabolic Diseases Study Group, Department of Internal Medicine, Universidad del Cauca, Carrera 5 # 13N-36, Popayán, Cauca, Colombia.
Background And Aim:
To provide an update on the usefulness of basal insulin in patients with type 2 diabetes mellitus.
Methods:
We conducted a literature search using PubMed and MEDLINE, BIOSIS, Scopus, EMBASE, ClinicalTrials.gov, Google Scholar, and Springer Online Archives Collection until June 2021.
Results:
All basal insulins are similar in efficacy, with only small differences among them in terms of the risk of hypoglycemia.
Conclusions:
For type 2 diabetes mellitus, all basal insulins have a similar efficacy, with some advantage of Glar-300 and Deg-100 in reducing the risk of hypoglycemia compared to Glar-100.
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