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Updated: Oct 15, 2025

Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans
Published on: December 19, 2014
Disseminated Cryptococcus neoformans infection associated to COVID-19
Diana Alegre-González1, Sabina Herrera2, Javier Bernal2
1Department of Internal Medicine, Hospital San Pedro, Logroño, 26007, Spain.
Abstract:
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a novel coronavirus associated with immune dysregulation. The use of immunosuppressant drugs as part of COVID-19 treatment (such as Tocilizumab or high -dose corticosteroids) increases the risk of opportunistic infections. Here we present a case of a patient without prior immunosuppression that developed a serious fungal infection after the use of high dose corticosteroids in the setting of severe COVID-19 and cryptogenic organizing pneumonia.
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