Dealing with floppy iris syndrome
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Updated: Oct 15, 2025

Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Sally S E Park1, Sam Wilkinson, Nick Mamalis
1John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
Purpose Of Review:
The aim of this study was to review and summarize recent findings and advancements regarding intraoperative floppy iris syndrome (IFIS). Although many improvements have been made for the management of IFIS, it remains a challenging condition for surgeons. An understanding of the syndrome as well as the multitude of tools to mitigate risk of complication is important for surgeons operating on high-risk patients.
Recent Findings:
A variety of management approaches have been modified and improved or further supported with new data, such as intracameral compounds, intraoperative devices and surgical techniques.
Summary:
An understanding of risk factors is important for the identification of at-risk patients. A variety of approaches can greatly reduce incidence of IFIS complications. Multiple management strategies should be utilized to further reduce risk during these difficult surgeries.
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