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Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
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Task-based and Resting State Functional MRI in Children.

Mohit Maheshwari1, Tejaswini Deshmukh1, Eric C Leuthardt2

  • 1Department of Radiology, Medical College of Wisconsin, Children's Wisconsin, MS - 721, 9000 W Wisconsin Avenue, Milwaukee, WI 53226, USA.

Magnetic Resonance Imaging Clinics of North America
|October 31, 2021
PubMed
Summary
This summary is machine-generated.

Task-based functional MRI (fMRI) offers significant benefits for pediatric presurgical planning, similar to adults. This review details necessary adaptations for pediatric fMRI, covering motor and language systems, resting-state fMRI, and potential challenges.

Keywords:
BOLDPresurgical planningResting state fMRITask fMRI

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Area of Science:

  • Neuroimaging
  • Pediatric Neurology
  • Neurosurgery

Background:

  • Functional MRI (fMRI) is a crucial tool for presurgical planning in adults.
  • Increasing application of task-based fMRI in pediatric populations for similar planning benefits.
  • Need for specialized adaptations when applying fMRI in children.

Purpose of the Study:

  • To review essential adaptations for successful pediatric task-based fMRI.
  • To discuss the application of resting-state fMRI in children.
  • To identify common challenges and relevant networks for pediatric neuroimaging.

Main Methods:

  • Review of task-based functional MRI (fMRI) adaptations for pediatric motor and language systems.
  • Evaluation of resting-state fMRI (rs-fMRI) methodology and its pros and cons in pediatrics.
  • Discussion of common pitfalls and other relevant brain networks for special pediatric cases.

Main Results:

  • Task-based fMRI requires specific modifications for effective use in pediatric presurgical planning.
  • Resting-state fMRI presents distinct advantages and disadvantages compared to task-based fMRI in children.
  • Identification of key challenges and alternative neuroimaging targets for pediatric neurosurgical guidance.

Conclusions:

  • Task-based fMRI, with appropriate adaptations, is a valuable presurgical tool for pediatric patients.
  • Resting-state fMRI offers a complementary approach with unique benefits for pediatric neuroimaging.
  • Addressing specific challenges and considering diverse networks enhances the utility of fMRI in pediatric neurosurgery.