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Intraparenchymal Schwannoma: A Rare Entity
Michael S Vaphiades1, James Hackney2
1Departments of Ophthalmology, University of Alabama, Birmingham, Alabama, USA.
Neuro-Ophthalmology (Aeolus Press)
|November 1, 2021
Summary
A rare intraparenchymal schwannoma caused a 60-year-old woman's headaches and vision loss. This case highlights the importance of considering unusual brain tumors in differential diagnoses.
Area of Science:
- Neuro-oncology
- Neuropathology
Background:
- Intraparenchymal schwannomas are rare primary brain tumors originating from Schwann cells within the brain parenchyma.
- They are distinct from the more common schwannomas that arise from cranial or spinal nerve roots.
Observation:
- A 60-year-old woman presented with symptoms including headaches, transient visual obscurations, and pulsatile tinnitus.
- Physical examination revealed Frisén grade 4 papilledema, indicating increased intracranial pressure.
- Brain magnetic resonance imaging (MRI) demonstrated a large, subfrontal cystic mass with characteristic ring enhancement.
Findings:
- Histopathological examination of the resected tumor confirmed the diagnosis of an intraparenchymal schwannoma.
- The tumor's location and imaging features were consistent with its rare intraparenchymal origin.
Implications:
- This case underscores the diagnostic challenge posed by rare intraparenchymal brain tumors.
- Accurate diagnosis and surgical management are crucial for favorable outcomes in patients with these uncommon neoplasms.
- Further research into the pathogenesis and optimal treatment strategies for intraparenchymal schwannomas is warranted.

