A Case of Progressive Supranuclear Palsy-like Syndrome: Aetiology Revealed

In 2015, we published an enigmatic case in Neuro-Ophthalmology regarding an 18-year-old woman who underwent an initially uneventful ascending aortic aneurysm repair. After 48 h, she developed a progressive supranuclear palsy-like syndrome with no findings on magnetic resonance imaging (MRI), MRI tractography, or functional MRI which correlated with this syndrome. After following our patient over the ensuing years, it became clear that the likely aetiology of these neurologic deficits was the profound deep hypothermia associated with her aortic aneurysm repair.