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Related Concept Videos

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Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Drugs Used in Lower Respiratory Disorders: Overview01:17

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Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
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[Inhalotherapy: Recommendations for Argentina 2021].

Martín Sívori1, Ana Balanzat2, Enrique Barimboim3

  • 1Unidad de Neumotisiología, Hospital Dr. J.M. Ramos Mejía y Centro Universitario de Neumonología, UBA, Buenos Aires, Argentina.

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This study provides Argentinian recommendations for inhaled devices (IDs) to improve respiratory disease management. It details device selection based on patient needs and correct usage to enhance treatment efficacy.

Keywords:
aerochamberdry powder inhalersmetered dose inhalersnebulization

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Area of Science:

  • Pulmonary Medicine
  • Respiratory Device Technology
  • Clinical Pharmacy

Background:

  • Inhaled devices (IDs) are crucial for managing obstructive respiratory diseases, but correct usage is often a challenge.
  • Argentina currently lacks specific recommendations for inhalation therapy, leading to potential inconsistencies in patient care.
  • Recent global health events, like the SARS-CoV-2 pandemic, have influenced the use of certain inhalation methods.

Purpose of the Study:

  • To establish local recommendations for the prescription and use of inhaled devices in Argentina.
  • To provide a comprehensive review of various inhaled devices, including their biophysical principles, indications, and limitations.
  • To guide healthcare professionals in selecting the most appropriate inhaled device for individual patients.

Main Methods:

  • A systematic review of different inhaled devices was conducted, evaluating their technical aspects and clinical applications.
  • Information on device-specific techniques, common errors, cleaning, and maintenance was compiled.
  • Consideration was given to device use in specific populations, such as cystic fibrosis patients and those on mechanical ventilation.

Main Results:

  • Nebulization should be reserved for specific drugs or when other devices are ineffective, and is not recommended during the SARS-CoV-2 pandemic.
  • Metered-dose inhalers (MDIs) should always be used with an aerochamber to improve lung deposition and reduce adverse events.
  • Device selection should differentiate between patients needing an aerochamber (low inspiratory flow) and those suitable for dry powder inhalers (high inspiratory flow).

Conclusions:

  • The choice of an inhaled device is multifactorial, depending on the patient's clinical status, age, experience, preference, and drug availability.
  • Implementing standardized recommendations for inhaled device use can optimize treatment efficacy and patient outcomes in Argentina.
  • Proper patient education on the correct use and maintenance of inhaled devices is essential for effective respiratory disease management.