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Interplay between ADP-ribosyltransferases and essential cell signaling pathways controls cellular responses

Flurina Boehi1,2, Patrick Manetsch1,3, Michael O Hottiger4

  • 1Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.

Cell Discovery
|November 2, 2021
PubMed
Summary

ADP-ribosylation, a protein modification, regulates cell signaling. This review explores how ADP-ribosyltransferases interact with key pathways like NF-κB and MAPK, influencing cellular responses.

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