Related Experiment Video
Updated: Oct 14, 2025

Author Spotlight: Implementing the Enhanced Recovery After Surgery Concept in Rehabilitation Following Anterior Cruciate Ligament Reconstruction
Published on: March 1, 2024
Nurse-driven early rehabilitation protocol for critically ill children
Chanapai Chaiyakulsil1, Panitnard Thippanate2
1Division of Pediatric Critical Care, Department of Pediatrics, Faculty of Medicine, Thammasat University Hospital, Thammasat University, Pathumthani, Thailand.
Insights
A nurse-driven early mobilization protocol significantly reduced motor dysfunction in critically ill children. This intervention proved feasible and safe, improving outcomes without increasing intensive care unit stays or ventilator days.
Area of Science:
- Pediatric critical care medicine
- Rehabilitation therapy
- Nursing science
Background:
- Physical impairment is a significant cause of morbidity in children who survive intensive care.
- Early mobilization is crucial for recovery and reducing long-term complications in pediatric patients.
Purpose of the Study:
- To evaluate the effectiveness of a nurse-driven protocol for early mobilization in critically ill children.
- To assess the protocol's impact on motor dysfunction, pediatric intensive care unit (PICU) length of stay, and ventilator days.
- To determine the safety of the early mobilization protocol, monitoring for injuries and cardiorespiratory instability.
Main Methods:
- A retrospective interrupted time-series study design comparing pre-implementation (Jan-June 2020) and post-implementation (July-Dec 2020) phases.
- Utilized the Functional Status Scale's motor function domain to assess motor dysfunction post-PICU discharge.
- Compared outcomes between a control group and a group receiving the nurse-driven early mobilization protocol.
Main Results:
- A statistically significant reduction in motor dysfunction was observed post-protocol implementation (64.0% vs 36.0%, P = 0.044), with an absolute risk reduction of 28%.
- The number needed to treat was 3.6 children to prevent one instance of motor dysfunction.
- No significant differences were found in median ventilator days, PICU length of stay, or hospital length of stay. No complications were reported.
Conclusions:
- A nurse-driven protocol for early mobilization is feasible in the pediatric intensive care unit setting.
- This protocol can be effective in reducing motor dysfunction in critically ill children following intensive care.
- The intervention demonstrated a favorable safety profile without adverse events.
Background:
Physical impairment is a major morbidity in children surviving intensive care. The main objective of this study was to evaluate the effectiveness of a nurse-driven protocol in the early mobilization of critically ill children in terms of reduction of motor dysfunction, pediatric intensive care unit stays, and ventilator days. The secondary objective was to evaluate safety, in terms of injury, dislodgement of medical devices, and cardiorespiratory instability attributable to the intervention.
Methods:
The early rehabilitation intervention was initiated in July 2020. This retrospective interrupted time-series study was divided into the pre-implementation phase (January-June 2020) and the post-implementation phase (July-December 2020). The motor function domain of the Functional Status Scale was used to define the motor dysfunction after pediatric intensive care unit discharge.
Results:
Twenty-five children were allocated in each group. The median age of the whole cohort was 11.5 months and approximately 58% of the population was male. The baseline characteristics of both groups were not statistically significant. There was a statistically significant reduction in motor dysfunction after protocol implementation (64.0% vs 36.0%; P = 0.044) with an absolute risk reduction of 28%. The number needed to treat was 3.6 children. There were no statistically significant differences in the median ventilator days, length of stay in the intensive care unit, and hospital length of stay. No complications were found.
Conclusions:
A nurse-driven protocol for the early mobilization of critically ill children was feasible and could be effective in reducing post-intensive care motor dysfunction.
More Related Videos
Related Concept Videos
Acute Kidney Injury VI: Nursing Management
Acute Kidney Injury V: Interprofessional Care
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Acute Kidney Injury I: Introduction
Restorative Care
Acute Kidney Injury IV: Diagnostic Studies and Prevention

