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Chromium-based metal organic framework for pipette tip micro-solid phase extraction: an effective approach for
Massoud Kaykhaii1,2, Sayyed Hossein Hashemi3, Fariba Andarz4
1Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, 98136-674, Iran. kaykhaii@chem.usb.ac.ir.
Background:
A chromium-based metal organic framework was synthesized and employed as an efficient sorbent for pipette tip micro-solid phase extraction and preconcentration of parabens from wastewater and shampoo samples up to sub-ppb level before their spectrophotometric analysis.
Results:
Factors affecting preconcentration including volume and type of solvent, amount of sorbent, number of extraction, and volume and pH of samples were optimized employing one-variable-at-a-time and response surface methodology. Obtained analytical characteristics of the method proves its usefulness for analysis of real samples. Linear range of the method for parabens was 1.0-200.0 μg/L. Detection limit of the protocol was 0.24 µg/L for propyl paraben and 0.25 µg/L for methyl paraben. Reproducibility of the protocol defined as % RSD was better than 5.78%. Synthesized adsorbent can be re-used for at least 20 extractions.
Conclusion:
The method showed a good detection limit and precision for determination of methyl- and propyl-paraben in wastewater and shampoo samples.
