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Good's syndrome with diffuse panbronchiolitis as the prominent manifestation: A case and literature review
Tian Luo1,2, Lile Wang1,2, Daiyan Fu1,2
1The Third Department of Pulmonary and Critical Care Medicine The First Affiliated Hospital of Hunan Normal University Changsha China.
Abstract:
Good's syndrome (GS) is characterized by thymoma combined with adult-onset immunodeficiency. Diffuse panbronchiolitis (DPB) is a chronic inflammatory airway disease, which predominantly affects East Asians. Japanese scholars have reported extensively about GS combined with DPB or DPB-like pulmonary manifestation. However, such reports are rare in China. We report here a case of GS in China with DPB as the prominent manifestation and carry out a literature review accordingly. Our review indicates that in adults with DPB-like clinical manifestations, thymic lesions should be excluded and related immune function tests should be performed to exclude GS to avoid missed diagnosis and misdiagnosis.
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