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Spinal Manipulative Therapy for Acute Neck Pain: A Systematic Review and Meta-Analysis of Randomised Controlled
Aleksander Chaibi1,2, Knut Stavem3,4,5, Michael Bjørn Russell1,3
1Head and Neck Research Group, Division for Research and Innovation, Akershus University Hospital, 1478 Oslo, Norway.
Journal of Clinical Medicine
|November 13, 2021
Summary
Spinal manipulative therapy (SMT) effectively reduces acute neck pain, offering a valuable treatment option. While generally safe with minor side effects, further high-quality research is needed to confirm its benefits.
Area of Science:
- Orthopedics
- Physical Therapy
- Pain Management
Background:
- Acute neck pain is a prevalent condition often managed with medication or manual therapy.
- General practitioners express reservations regarding manual therapy's efficacy and potential adverse events.
- Uncertainty exists regarding the optimal treatment strategies for acute neck pain.
Purpose of the Study:
- To systematically review randomized controlled trials (RCTs) evaluating spinal manipulative therapy (SMT) for acute neck pain.
- To assess the effectiveness and safety of SMT in managing acute neck pain.
- To synthesize evidence from existing RCTs to inform clinical practice.
Main Methods:
- A systematic review of original randomized controlled trials (RCTs) was conducted.
- Data extraction was performed in duplicate and findings tabulated.
- Study quality was assessed using the Cochrane Back and Neck (CBN) Risk of Bias tool, and evidence graded using GRADE criteria.
Main Results:
- Six RCTs were included in the review.
- A significant pooled effect size (SMT vs. controls) of -1.37 indicated strong effectiveness for SMT in reducing neck pain.
- One study demonstrated SMT's superiority over ketorolac for acute neck pain relief one day post-treatment.
Conclusions:
- Spinal manipulative therapy (SMT), whether standalone or combined with other treatments, is effective for acute neck pain.
- Minor transient adverse events like increased pain and headache were reported, with no serious adverse events noted.
- Limitations include the small number and variable quality of studies, pragmatic designs, and high heterogeneity, necessitating further research.

