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Liquid metal-polymer conductor-based wireless, battery-free epidermal patch.

Lei Mou1, Yong Xia2, Xingyu Jiang1

  • 1Department of Clinical Laboratory, Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, Liwan District, Guangzhou, Guangdong, 510150, PR China; Department of Biomedical Engineering, Southern University of Science and Technology, No 1088, Xueyuan Rd., Xili, Nanshan District, Shenzhen, Guangdong, 518055, PR China.

Biosensors & Bioelectronics
|November 13, 2021
PubMed
Summary
This summary is machine-generated.

A new wireless epidermal patch uses liquid metal-polymer conductors for real-time sweat analysis. This wearable technology enables non-invasive health monitoring by detecting metabolites and electrolytes.

Keywords:
MicrofluidicsStretchable conductorSweat sensorWearable sensorWireless communication

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Area of Science:

  • Materials Science and Engineering
  • Biomedical Engineering
  • Analytical Chemistry

Background:

  • Wearable epidermal patches offer a promising avenue for real-time, non-invasive biological signal monitoring.
  • Existing technologies face challenges in seamless integration, wireless communication, and comprehensive analyte detection.
  • Development of advanced conductive materials is crucial for enhancing the functionality of epidermal sensors.

Purpose of the Study:

  • To develop and characterize a novel wireless epidermal patch utilizing liquid metal-polymer conductors (LMPC).
  • To demonstrate the capability of LMPC-based antennas and wires for wireless power supply and signal communication.
  • To evaluate the analytical performance of the LMPC-based epidermal patch for multiplexed sweat analysis.

Main Methods:

  • Fabrication of a novel conductive material, liquid metal-polymer conductors (LMPC), through casting and peeling techniques.
  • Integration of LMPC to create printable antennas and wires for wireless functionalities.
  • Development of an epidermal patch sensor for simultaneous detection of metabolites, electrolytes, and urea in sweat.

Main Results:

  • The developed LMPC material exhibits excellent stretchability, repeatability, and biocompatibility.
  • LMPC-based antennas and wires successfully enabled wireless power transfer and data communication for the epidermal patch.
  • The epidermal patch demonstrated high analytical performance for sweat analysis, including low limits of detection, rapid response times, and multiplex detection capabilities.

Conclusions:

  • The LMPC-based wireless epidermal patch represents a significant advancement in wearable sensing technology.
  • This technology facilitates non-invasive, real-time monitoring of key biomarkers in sweat.
  • The developed epidermal patch holds substantial potential for widespread application in personal health diagnostics and continuous health monitoring.