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Updated: Oct 13, 2025

Focal Laser Ablation of Prostate Cancer: An Office Procedure
Published on: March 30, 2021
Evolution of Focal Therapy in Prostate Cancer: Past, Present, and Future
Rohith Arcot1, Thomas J Polascik1
1Division of Urology, Duke University Medical Center, Duke University, Duke Cancer Center, 20 Duke Medicine Circle, Durham, NC 27710, USA.
Abstract:
Organ sparing approaches for the management of localized prostate cancer were developed in part to overcome the morbidity associated with standard, whole gland treatment options. The first description of focal therapy was now over two decades ago and since that time much has changed. The evolution of patient selection, the approach to ablation, and surveillance after focal therapy have mirrored the technologic advancements in the field as well as the improved understanding of the biology of low-grade, low-risk prostate cancer. This review presents the evidence for the basis of focal therapy from the past to the present and future endeavors.
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