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Updated: Oct 13, 2025

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
Published on: August 24, 2015
Scabies in a 14-year-old girl with superficial epidermolytic ichthyosis
Igor Vázquez-Osorio1, Noelia Moreiras-Arias1, Patricia Pérez-Feal1
1Department of Dermatology, Hospital Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Abstract:
A 14-year-old girl who reported generalized scaling and hyperkeratosis since age 1 year presented with severe pruritus of several months' duration. Scabies mites were detected, and molecular genetic analysis subsequently revealed a rare pathogenic variant in the keratin 2 (KRT2) gene, confirming a diagnosis of superficial epidermolytic ichthyosis. Treatment with oral ivermectin led to complete remission of symptoms. Disorders of keratinization can mimic clinical signs of scabies, leading to a delay in diagnosis.
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