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From Mass to Flow: Emerging Sepsis Diagnostics Based on Flow Cytometry Analysis of Neutrophils

Franck Verdonk1,2, Joe L Hsu3, Brice Gaudilliere4

  • 1Department of Anesthesiology and Intensive Care Hôpital Saint-Antoine Paris, France.

American Journal of Respiratory and Critical Care Medicine
|November 17, 2021
PubMed
Abstract

No abstract available in PubMed .

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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