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Related Concept Videos

Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
543
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Irritable Bowel Syndrome III: Medical and Nursing Management01:30

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Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
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Chronic Bowel Disorders: Introduction01:17

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Postoperative Ileus Murine Model
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Postinfection Irritable Bowel Syndrome.

Uday C Ghoshal1

  • 1Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Gut and Liver
|November 18, 2021
PubMed
Summary

Post-infection irritable bowel syndrome (PI-IBS) affects 11.5% of patients after acute gastroenteritis (AGE). PI-IBS suggests an organic basis for some IBS cases, with various risk factors identified.

Area of Science:

  • Gastroenterology
  • Microbiology
  • Psychiatry

Background:

  • Acute gastroenteritis (AGE) can lead to new-onset irritable bowel syndrome (IBS), termed post-infectious IBS (PI-IBS).
  • PI-IBS serves as a model for understanding the organic underpinnings of IBS in a subset of patients.
  • The pooled prevalence of PI-IBS following AGE is estimated at 11.5%.

Purpose of the Study:

  • To summarize the prevalence, risk factors, clinical presentation, and management of PI-IBS.
  • To highlight PI-IBS as a model for IBS pathophysiology.
  • To identify areas for future research, particularly regarding treatment efficacy.

Main Methods:

  • Review of existing literature on PI-IBS following AGE.
  • Analysis of pooled prevalence data.
Keywords:
COVID-19DysenteryEnteritisGastrointestinal disordersTropical sprue

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  • Identification and summary of associated risk factors and clinical features.

    • Main Results:

    • A significant subset of patients develop PI-IBS after AGE, with a pooled prevalence of 11.5%.
    • Numerous factors increase PI-IBS risk, including female sex, younger age, smoking, AGE severity, psychological factors, and antibiotic use.
    • PI-IBS commonly presents as diarrhea-predominant or mixed IBS, often overlapping with other functional gastrointestinal disorders.

    Conclusions:

    • PI-IBS is a recognized condition following AGE, indicating a potential organic basis for IBS.
    • Understanding risk factors is crucial for identifying at-risk individuals.
    • Further randomized controlled trials are needed to establish effective drug treatments for PI-IBS.