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A review of controlled release from cyclodextrins: release methods, release systems and application
Yan Feng1, Shuangdi Chen1, Zhaofeng Li1,2,3
1School of Food Science and Technology, Jiangnan University, Wuxi, People's Republic of China.
Critical Reviews in Food Science and Nutrition
|November 19, 2021
Summary
Cyclodextrin (CD) inclusion complexes enable controlled release of molecules for diverse industries. This review details CD-based systems, enhancing substance bioavailability and applications.
Area of Science:
- Supramolecular Chemistry
- Materials Science
Background:
- Controlled release of guest molecules from cyclodextrin (CD) inclusion complexes is crucial for industries like medicine, food, and agriculture.
- Controlled release strategies include immediate, sustained, and targeted release methods.
Approach:
- This review systematically examines the principles of CD-based controlled release systems.
- It covers common systems such as CD inclusion complexes, CD coupling, supramolecular hydrogels, and supramolecular micelles.
Key Points:
- CD inclusion complexes offer versatile platforms for modulating guest molecule release.
- Various supramolecular architectures based on CDs are employed for controlled release applications.
- Understanding these systems is key to improving the efficacy of active substances.
Conclusions:
- CD-based controlled release systems are vital for numerous industrial applications.
- This review provides a theoretical foundation for advancing CD technology.
- Further development can broaden the application scope and bioavailability of encapsulated substances.
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