Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Toxic Reactions: Overview01:26

Toxic Reactions: Overview

1.2K
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
1.2K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

2.6K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.6K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

4.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.4K
Effects of Chemicals: Overview01:27

Effects of Chemicals: Overview

1.5K
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
1.5K
Skin Cancer01:30

Skin Cancer

4.9K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.9K
Local Anesthetics: Adverse Effects01:12

Local Anesthetics: Adverse Effects

519
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
519

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Role of genomic science in males with breast cancer.

Nursing·2026
Same author

Beyond Checking a Box: Embracing and Navigating Ethical Authorship.

Clinical journal of oncology nursing·2026
Same author

Errors in Germline Biomarker Testing: Significant Consequences and Missed Opportunities for Cancer Control in Patients and Their Families.

Cancer journal (Sudbury, Mass.)·2026
Same author

Quality and Safety Imperatives in the Identification and Management of Hereditary Cancer Syndromes.

Seminars in oncology nursing·2026
Same author

Educating Nurses for Genomics-Informed Cancer Care: Strengthening the Current and Future Workforce.

Seminars in oncology nursing·2026
Same author

Seminal Editorial: Who We Are.

Clinical journal of oncology nursing·2025
Same journal

How Can Oncology Nurses Learn to See Beyond the Numbers?

Clinical journal of oncology nursing·2026
Same journal

Care of Patients Receiving Abemaciclib: Results From Clinical Trials and a Healthcare Provider Survey.

Clinical journal of oncology nursing·2026
Same journal

The Role of Oncology Nurses in National Breast and Cervical Cancer Screening Programs.

Clinical journal of oncology nursing·2026
Same journal

Technology-Assisted Nutrition Education Program for Patients With Cancer Undergoing Gastrectomy: A Quasi-Experimental Study.

Clinical journal of oncology nursing·2026
Same journal

The Hidden Biology of Life Experience: Using SEMOARS + GEM and Precision Health for Psychoneurologic Symptoms in Hematologic Malignancies.

Clinical journal of oncology nursing·2026
Same journal

GLP-1 Medications in Oncology Nursing Practice.

Clinical journal of oncology nursing·2026
See all related articles

Related Experiment Video

Updated: Oct 12, 2025

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis
07:08

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Published on: August 31, 2022

1.8K

Skin Toxicities: Common Side Effect.

Suzanne M Mahon1, Ellen Carr2

  • 1Saint Louis University.

Clinical Journal of Oncology Nursing
|November 20, 2021
PubMed
Summary
This summary is machine-generated.

Cancer treatments like chemotherapy cause frequent skin toxicities, including rashes and hair loss, affecting up to 90% of patients. Evidence-based practices guide the standard of care for managing these common side effects.

Keywords:
cancerlong-term side effectsside effectssurvivorship caresymptoms

More Related Videos

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

660
Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

1.2K

Related Experiment Videos

Last Updated: Oct 12, 2025

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis
07:08

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Published on: August 31, 2022

1.8K
A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

660
Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

1.2K

Area of Science:

  • Oncology
  • Dermatology

Background:

  • Skin toxicities are a common and distressing side effect of antineoplastic therapies.
  • These toxicities frequently manifest as rashes, hand-foot skin reaction/syndrome, and hair loss.
  • Up to 90% of patients undergoing cancer treatment experience some form of skin toxicity.

Purpose of the Study:

  • To outline the evidence-based practices for managing cancer treatment-related skin toxicities.
  • To highlight the prevalence and common presentations of skin toxicities.

Main Methods:

  • Review of established evidence-based practices for skin toxicity management.
  • Identification of common skin toxicities associated with chemotherapy and targeted therapies.

Main Results:

  • Standards of care for skin toxicities are grounded in evidence-based practice.
  • Chemotherapy and targeted therapies are primary causes of these adverse skin reactions.
  • Manifestations include various rashes, hand-foot syndrome, and alopecia.

Conclusions:

  • Effective management strategies for skin toxicities are crucial for patient well-being during cancer treatment.
  • Adherence to evidence-based guidelines ensures optimal care for patients experiencing these side effects.