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In vitro and molecular docking analysis of chalconeimine derivatives with α-glucosidase

R Asaithambi1, C Palanivel1

  • 1PG and Research Dept. of Chemistry, Government Arts College, C. Mutlur, Chidambaram - 608102, Tamilnadu, India.

Bioinformation
|November 22, 2021
PubMed

Keywords:
antioxidantdiphenyl-picrylhydrazine (DPPH)green synthesisnanoparticles of TiO2 ZnO

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α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...
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