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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Papillary Dermis01:11

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Reticular Dermis01:15

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

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Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Dermatoscopy.

Christina Ring1, Nathan Cox1, Jason B Lee1

  • 1Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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Dermatoscopes enhance skin disease diagnosis by revealing subsurface structures. While widely adopted, their impact on biopsy rates, costs, and patient outcomes requires further investigation.

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Area of Science:

  • Dermatology and diagnostic imaging.
  • Medical technology assessment.

Background:

  • Dermatoscopes are increasingly popular tools for dermatologists.
  • Initially used for melanoma diagnosis, their application has broadened.
  • Current use extends to inflammatory, infectious, and vascular skin conditions.

Purpose of the Study:

  • To review the expanding role of dermatoscopy in dermatology.
  • To explore emerging subspecialties like inflammedoscopy, trichoscopy, and onychoscopy.
  • To discuss the future integration of artificial intelligence in dermatoscopy.
  • To assess the overall impact of widespread dermatoscopy use.

Main Methods:

  • Review of current dermatological literature and clinical practices.
  • Analysis of the evolution and adoption trends of dermatoscopy.
  • Exploration of specialized dermatoscopic fields and future technological integration.

Main Results:

  • Dermatoscopy is now a near-universally adopted technique by dermatologists.
  • Specialized branches of dermatoscopy have emerged for various conditions.
  • Artificial intelligence integration is anticipated to enhance objectivity and accuracy.
  • The definitive impact on biopsy rates, healthcare costs, and patient outcomes remains undetermined.

Conclusions:

  • Dermatoscopy has evolved from a specialized tool to a fundamental diagnostic technique.
  • Future advancements, particularly AI, promise to further refine its capabilities.
  • Further research is crucial to quantify the clinical and economic benefits of widespread dermatoscopy adoption.