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Updated: Oct 12, 2025

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
[Pulmonary tumor embolism]
Saranda Sahiti1, Samuel Rotman2,3, Malik Benmachiche1
1Service de médecine interne, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Abstract:
Pulmonary tumor embolism is characterized by the occlusion of pulmonary vessels by tumor clots, which can be found in the proximal arteries (macro-embolism) or the small vessels (micro-embolism). The clinical presentation is mainly a progressive dyspnea associated with pulmonary hypertension and subacute cor pulmonale. The diagnosis is difficult, mostly made post-mortem. It is rarely obtained through a combination of multiple diagnostic tests (chest CT, ventilation-perfusion scanning, pulmonary artery cytology, biopsy). Treatment is based on the one of the underlying cancer. The prognosis is poor, and patients usually die within weeks to months. It is a rare cause of pulmonary hypertension that must be considered even without a prior oncological diagnosis.
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