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Updated: Oct 12, 2025

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
Central and Peripheral Oxygen Distribution in Two Different Modes of Interval Training
Korbinian Sebastian Hermann Ksoll1,2, Alexander Mühlberger3, Fabian Stöcker3
1Institute of Sport Sciences, Department of Human Sciences, Universität der Bundeswehr Munich, 85579 Neubiberg, Germany.
Adjusting interval duration in high-intensity interval training (HIIT) impacts physiological responses. Both long (HIIT3m) and short (HIIT30s) intervals can optimize training, with duration influencing cardiovascular stress and potential adaptations.
Area of Science:
- Exercise Physiology
- Sports Science
- Cardiovascular Research
Background:
- High-intensity interval training (HIIT) effectiveness can be modulated by interval duration.
- Optimizing oxygen uptake, cardiac output, and local oxygen supply requires careful adjustment of interval and rest periods.
- Understanding the physiological impact of different HIIT protocols is crucial for personalized training.
Purpose of the Study:
- To compare physiological responses, including oxygen uptake and cardiac output, between long-interval HIIT (HIIT3m) and short-interval HIIT (HIIT30s).
- To analyze the effects of interval duration on cardiopulmonary and muscle tissue stress under matched work rates and duration.
- To determine if different interval durations elicit comparable overall physiological adaptations.
Main Methods:
- 24 participants completed both HIIT3m (3 min work, 3 min active rest) and HIIT30s (30 s work, 30 s active rest) protocols in a randomized order.
- Work intensity was set at 80% of power output at VO2peak, and relief intensity at 85% of power output at the gas exchange threshold.
- Spirometry, impedance cardiography, and near-infrared spectroscopy were employed to measure physiological variables.
Main Results:
- While HIIT3m had shorter durations above the gas exchange threshold, both protocols showed similar average fractional utilization of VO2peak.
- HIIT3m induced higher cardiovascular responses (VO2 and cardiac output) during loaded intervals.
- No significant differences in local hemodynamics were observed; average physiological responses were similar due to incomplete recovery in HIIT30s and large response amplitudes in HIIT3m.
Conclusions:
- Despite lower acute cardiovascular stress in HIIT30s, short submaximal intervals may induce comparable microvascular and metabolic adaptations to HIIT3m.
- Interval duration is a key variable for tailoring HIIT to specific athlete or patient needs and training goals.
- Both HIIT3m and HIIT30s can be effective, but the choice impacts acute cardiovascular load and recovery dynamics.
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