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Perioperative Anaphylaxis.

Mitchell M Pitlick1, Gerald W Volcheck1

  • 1Division of Allergic Diseases, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA.

Immunology and Allergy Clinics of North America
|November 26, 2021
PubMed
Summary
This summary is machine-generated.

Perioperative anaphylaxis, a severe allergic reaction during surgery, is often caused by common medications and materials. Prompt allergy evaluation and management are crucial for patient safety.

Keywords:
AnaphylaxisAnesthesiaHypersensitivity reactionIntraoperativePerioperative

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Area of Science:

  • Anesthesiology
  • Allergy and Immunology
  • Critical Care Medicine

Background:

  • Perioperative anaphylaxis is a critical, yet under-recognized, surgical complication.
  • It poses significant risks, including mortality, if not promptly identified and managed.

Purpose of the Study:

  • To review current understanding of perioperative anaphylaxis.
  • To update on its epidemiology, pathogenesis, and common triggers.
  • To outline essential management strategies, emphasizing allergy assessment.

Main Methods:

  • Literature review of perioperative anaphylaxis.
  • Synthesis of data on epidemiology and pathogenesis.
  • Discussion of causative agents and diagnostic approaches.

Main Results:

  • Common triggers include antibiotics, neuromuscular blockers, dyes, latex, and disinfectants.
  • Understanding pathogenesis aids in identifying at-risk patients.
  • Comprehensive allergy evaluation is key to diagnosis and prevention.

Conclusions:

  • Perioperative anaphylaxis requires heightened awareness among healthcare providers.
  • Early recognition and thorough allergy evaluation are vital for effective management.
  • Proactive strategies can mitigate the risks associated with this severe adverse event.