Autoeczematization: A Strange Id Reaction of the Skin

Autoeczematization, or id reaction, is a disseminated eczematous reaction that occurs due to a release of antigen(s) after exposure to a primary stimulus, with the eczema spreading to a site distant from the original one. This seemingly perplexing generalization most commonly is associated with stasis dermatitis or tinea pedis, though it may be caused by a wide variety of other disorders. We postulate that T cells are reactive to keratinocyte antigens that are produced during keratinocyte damage, which induce this autoeczematization. Studies with current technology are needed to facilitate further understanding of this phenomenon.