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Prevalence and Clinical Characteristics of Lacunar Stroke: A Hospital-Based Study
Mohammed A Aldriweesh1,2, Waleed A Alluhidan3, Bayan A Al Bdah2
1College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 14611, Saudi Arabia.
Insights
Lacunar stroke (LS) is common, affecting 35.5% of ischemic stroke patients. LS patients had lower admission severity scores and shorter hospital stays, indicating better short-term outcomes.
Area of Science:
- Neurology
- Cardiovascular Research
- Public Health
Background:
- Lacunar stroke (LS) accounts for 25% of ischemic strokes, causing significant long-term health and economic burdens.
- Understanding the characteristics and outcomes of LS compared to other ischemic stroke subtypes is crucial for effective management.
Purpose of the Study:
- To investigate and compare lacunar strokes (LS) with non-lacunar ischemic strokes.
- To identify predictors and short-term outcomes of LS in a tertiary academic center.
Main Methods:
- Retrospective review of 989 ischemic stroke patients admitted between February 2016 and July 2019.
- Comparison of LS patients with other TOAST subtypes, excluding hemorrhagic stroke and stroke mimics.
- Regression analysis to determine LS predictors and outcomes.
Main Results:
- Lacunar stroke (LS) constituted 35.5% of all ischemic strokes in the cohort, with a majority of patients being male (71.9%).
- Lower National Institutes of Health Stroke Scale (NIHSS) scores on admission and a lack of cardiac disease history were identified as predictors for LS.
- LS patients exhibited lower NIHSS scores at discharge and shorter hospitalization durations compared to non-LS patients.
Conclusions:
- Lacunar stroke (LS) is a prevalent subtype of ischemic stroke within this patient cohort.
- LS is associated with less severe initial presentation and shorter hospital stays.
- Further research with extended follow-up is necessary to fully understand stroke recurrence, complications, and long-term outcomes for LS patients.
Abstract:
Lacunar stroke (LS) is responsible for one-quarter of the overall number of ischemic strokes with long-term complications and carries health and economic issues for patients and health care systems. Therefore, we aimed to investigate lacunar versus non-lacunar strokes in a tertiary academic center. From February 2016 to July 2019, all patients admitted to the stroke unit were retrospectively reviewed. We included LS patients and compared them to other TOAST subtypes. Hemorrhagic stroke and conditions mimicking stroke were excluded. Regression analysis was done to determine LS predictors and outcomes. A 35.5% rate of LS among 989 ischemic stroke patients was found. Most patients (71.9%) were males. Lower National Institutes of Health Stroke Scale (NIHSS) scores at admission and negative history for cardiac diseases were predictors for LS in our population. At discharge, LS patients had low NIHSS scores and shorter hospitalization periods compared to non-LS patients. In conclusion, LS was prevalent among ischemic stroke patients in our cohort. Future studies are highly needed with long follow-up intervals to identify the stroke recurrence, complications, and outcomes.
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