Synthetic biology as a tool to online teaching undergraduate level molecular biology

During the Covid-19 pandemic, all on-campus activities were required to be adapted to a distance-learning format, which was especially challenging for practical courses. Molecular biology is a mandatory course for biology undergraduates at Universidade Federal Fluminense. To overcome the impossibility of practical activities, we proposed problem-solving synthetic biology assignments to review and consolidate the knowledge acquired in the molecular biology course. A survey indicated that the synthetic biology challenges were effective to promote students' active learning and worked as a proper substitute to the practical classes.