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Vasospastic Angina: An Immune-related Adverse Event
Taku Kumamoto1, Hiroaki Kawano1, Masaya Kurobe1
1Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Abstract:
A 54-year-old Japanese woman was admitted to our ward because of recurrent chest pain at rest for 2 months. She had been treated with nivolumab, an immune checkpoint inhibitor for inoperable advanced hypopharyngeal cancer for 21 months. She had no chest pain after cessation of nivolumab treatment. Cardiac catheterization confirmed the presence of vasospastic angina. Benidipine 8 mg was started, and she had no chest pain even after resuming therapy with nivolumab. Vasospastic angina is an adverse effect of nivolumab.
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