Neonatal Resuscitation Research Priorities in Low- and Middle-Income Countries
Vivek V Shukla1,2, Somashekhar M Nimbalkar2
1University of Alabama at Birmingham, Birmingham, Alabama, USA.
Insights
This review highlights critical research gaps in neonatal resuscitation within low- and middle-income countries (LMICs). Addressing these gaps is vital for improving evidence-based resuscitation practices and reducing newborn mortality in these regions.
Area of Science:
- Neonatal Physiology
- Resuscitation Medicine
- Global Health
Background:
- Birth involves significant physiological shifts requiring timely interventions.
- Neonatal resuscitation is crucial for preventing mortality and morbidity.
- International guidelines exist but may not fully address LMIC contexts.
Purpose of the Study:
- To identify essential research areas for neonatal resuscitation in LMICs.
- To inform the development of context-specific, evidence-based guidelines for LMICs.
- To bridge the gap between global recommendations and local needs.
Main Methods:
- Literature review focusing on neonatal resuscitation research.
- Analysis of research output from low- and middle-income countries (LMICs).
- Identification of research priorities based on current evidence and identified gaps.
Main Results:
- Significant disparities exist in neonatal resuscitation research originating from LMICs.
- Key research areas are needed to tailor resuscitation practices to LMIC settings.
- Current evidence base is insufficient for LMIC-specific neonatal resuscitation recommendations.
Conclusions:
- Targeted research from LMICs is imperative for advancing neonatal resuscitation.
- Evidence-based guidelines must be adapted to the unique challenges faced in LMICs.
- Prioritizing research in LMICs will improve outcomes for neonates globally.
Abstract:
Several critical physiological changes occur during birth. Optimal and timely resuscitation is essential to avoid morbidity and mortality. The International Liaison Committee on Resuscitation (ILCOR) is a multinational committee that publishes evidence-based consensus and treatment recommendations for resuscitation in various scenarios including that for neonatal resuscitation. The majority of perinatal deaths occur in low- and middle-income countries (LMICs); however, there is limited research output from LMICs to generate evidence-based practice recommendations specific for LMICs. The current review identifies key areas of neonatal resuscitation-related research needed from LMICs to inform evidence-based resuscitation of neonates in LMICs.
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